Formulation of Brexin Tab
Piroxicam-ß-cyclodextrin
Brexin contains anti-inflammatory properties and provides pain relief. Basically, Brexin is a Piroxicam that pauses the chemical mediator’s production that causes inflammation and pain in the body. There are many health issues that Brexin deals with. Women also use this painkiller to treat menstrual cramps, as it is composed of Piroxicam beta-cyclodextrin. There are two forms of Brexin that you can use, tablet and powder form. Your doctor can prescribe a dose according to your pain intensity. The average dose for adults is 20 mg a day.
Brexin is also used to associated treatment for these conditions: : Ankylosing Spondylitis (AS), Osteoarthritis
(OA), Rheumatoid Arthritis. Carefully consider the potential benefits and risks of Piroxicam and other treatment options before deciding to use Piroxicam. Use the lowest effective dose for the
shortest duration consistent with individual patient treatment goals. Piroxicam
is used for relief of the signs and symptoms of osteoarthritis, for relief of
the signs and symptoms of rheumatoid arthritis.
Oedema, CHF, HTN, syncope, tachycardia; anorexia, abdominal pain, constipation, diarrhoea, dyspepsia, flatulence, heartburn, nausea, vomiting, dry mouth, esophagitis, gastritis, glossitis, haematemesis, melaena, stomatitis; anaemia, increased bleeding time, ecchymosis, eosinophilia, epistaxis, leucopenia, thrombocytopenia; cystitis, dysuria, haematuria, hyperkalaemia, interstitial nephritis, nephritic syndrome, oliguria/polyuria, proteinuria, renal failure; dizziness, headache, anxiety, asthenia, confusion, depression, dream abnormalities, drowsiness, insomnia, malaise, nervousness, paraesthesia, somnolence, tremors, vertigo; tinnitus, blurred vision; elevated LFT results; pruritus, rash, alopecia, bruising, desquamation, erythema, petechial rash, photosensitivity.
The dosage of Brexin depends on several factors, especially the patient’s medical history and current medical condition. A healthcare provider may adjust the drug dose depending on individual response and tolerability. However, some general guidelines for Brexin dosage are as follows:
- The usual recommended dose for adults is 20 mg once daily.
- For children, the dose is based on weight and is usually 0.5 mg per kg of body weight twice daily.
- For elderly patients, the dose may be reduced due to an increased risk of side effects.
Interaction
Increased risk of GI bleeding with anti-platelets and SSRIs. May exacerbate cardiac failure, reduce GFR and increase plasma glycoside levels. Increased risk of nephrotoxicity with ciclosporin and tacrolimus. Increased absorption with cimetidine. Increased risk of GI ulceration with corticosteroids. May interfere with the natriuretic action of diuretics. May displace other highly protein-bound drugs. May increase steady state plasma lithium levels. May antagonise the effect of antihypertensives. It may reduce the excretion of methotrexate, leading to acute toxicity. Increased risk of convulsions with quinolones. May interfere with mifepristone-mediated termination of pregnancy.
what are the alternative to Brexin Tab
Use any of the following alternatives to Brexin if this medication is unavailable to you:
- Acetaminophen such as Tylenol
- Non-NSAID pain relievers including aspirin, ibuprofen, or naproxen
- COX-2 inhibitors like Celebrex or Mobic
- Topical analgesics, including creams or gels such as Voltaren Gel and Lidocaine
- Steroids such as prednisone and dexamethasone.
Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Do not freeze liquid forms of this medication. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets.