Regesta Tab

Formulation of Regesta Tab

 Itopride 

Description of Regesta Tab

 Regesta Tab (Itopride’s) primary mechanism of action involves its ability to regulate gastrointestinal motility by acting on specific receptors in the digestive system. It is a mixed agonist of dopamine type-2 (D2) and antagonist of serotonin type-4 (5-HT4) receptors. By stimulating D2 receptors, itopride inhibits the release of acetylcholine, which reduces gastrointestinal motility. In contrast, its blockade of 5-HT4 receptors enhances gastrointestinal motility by increasing acetylcholine release. This dual action helps regulate the contractions of the stomach and intestines, improving gastric emptying and reducing symptoms associated with gastrointestinal disorders.

Uses of Regesta Tab

Regasta is an acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia, such as nausea and vomiting.

Investigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous).

Regasta is also used to associated treatment for these conditions: 

·       Abdominal Pain

·       Dyespepsia 

·       Functional Dyspepsia 

·       Gastroenteritis

·       Loss of Appetite

·       Nausea

·       Nausea and vomiting

·       Abdominal bloating

·       Pyrosis

·       Stomach discomfort

 

 

Side effects of Regesta Tab

Every medicine with active ingredients has side effects. However, these side effects are very rare. Most of the individuals don’t face the side effects.

  • Headache
  • Allergic reaction
  • Diarrhoea
  • Abdominal pain
  • Back and chest pain
  • Constipation

Regasta’s warnings include;

  • Be careful while using Regasta 50 mg Tablet without the doctor’s consent.
  • If you have allergy problems, then inform your doctor.
  • Share the list of all products (including allopathic and herbal) with your doctor.
  • Use Regasta 50 mg Tablet as long as your doctor prescribed it.
  • Do not change the dosage of Regasta 50 mg Tablet without the approval of the pharmacist or your doctor.
  • Consult your doctor before using Regasta 50 mg Tablet if you are pregnant or breastfeeding.

 

 

Dosages of Regesta Tab

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

  • For the treatment of gastrointestinal disorders such as nausea, vomiting, and diarrhea, the standard dosage is 50mg three times a day.
  • For the treatment of gastrointestinal symptoms resulting from chemotherapy or radiation therapy, such as nausea, vomiting, and diarrhea, the recommended dosage is 50mg four times a day.
  • Itopride Hydrochloride 50mg may also be used to treat other conditions, such as gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and gastroparesis. It’s crucial to follow your doctor’s instructions regarding dosage for these conditions, as it may vary.
  • It’s worth noting that dosage instructions may vary from person to person, depending on the severity of their condition. To ensure the safest and most effective treatment, it’s recommended to consult a medical professional or a pharmacist before taking Itopride Hydrochloride 50mg.

 

 

 

Drug Interaction

Following are the drug interactions for Itopride 50mg Tablet:

  • Itopride may interact with other dopamine antagonists, such as metoclopramide, leading to increased risk of extrapyramidal symptoms.
  • Concomitant use with anticholinergic drugs can reduce the effectiveness of Itopride.
  • Itopride can increase the absorption of certain medications, including antibiotics like erythromycin and antifungals like ketoconazole.
  • The absorption of Itopride may be reduced when taken with proton pump inhibitors (PPIs) like omeprazole.
  • Caution is advised when using Itopride with drugs that prolong QT interval, as it may increase the risk of cardiac arrhythmias.
  • Itopride may increase the effects of anticoagulants, such as warfarin, requiring close monitoring of coagulation parameters.
  • Interactions with other prokinetic agents like domperidone may increase the risk of adverse effects.

 

 

Storage

Disposal Itopride Hydrochloride 50mg should be stored in a cool, dry place away from direct sunlight and heat, ideally around room temperature (15-25°C).